Police are investigating the break in at an office unit of First Home Care on the Heathhall Industrial Estate.
It happened sometime between last Friday, July 7, and Monday.
Constable Ross Milligan at Dumfries said: “We are keen to hear from anyone who may have been on the Heathhall Industrial Estate over the weekend who might have seen or heard anything suspicious.”
Police can be contacted on the 101 number.