Four violins with a value of nearly £5500, a mandolin valued at around £800 and a banjo valued at around £600 were all stolen in the raid in Dalbeattie Road.
One of the violins dates back to 1890 and another to 1940, and both these violins are French in origin.
The break-in took place sometime between Monday May 4 and Friday May 8.
Anyone with information is asked to contact Police Scotland on 101.
Information can also be given through the independent charity Crimestoppers anonymously on 0800 555 111 or online at www.crimestoppers-uk.org.
Antique violins stolen
THIEVES have made off with an array of musical instruments from a house in Dumfries.
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